iPPI-DB

Inhibitors of Protein-Protein Interaction Database

iPPI-DB contains 1756 non-peptide inhibitors (iPPI) across 18 families of Protein-Protein Interactions. The chemical structures, the physicochemical and the pharmacological profiles of these iPPI are manually extracted from the literature and stored in iPPI-DB.

 By pharmacological criteria


Query iPPI-DB one PPI target at a time and optionally refine your search by choosing some specific pharmacological features, physicochemical characteristics for the compounds or extract only drug candidates.

Acknowledgments

 By chemical similarity


Sketch your molecule or copy/paste it as a SMILES, choose which fingerprint to use and fetch the 20 closest iPPI-DB compounds to your input along with their binding data.