Inhibitors of Protein-Protein Interaction Database

iPPI-DB contains 1756 non-peptide inhibitors (iPPI) across 18 families of Protein-Protein Interactions. The chemical structures, the physicochemical and the pharmacological profiles of these iPPI are manually extracted from the literature and stored in iPPI-DB.

 By pharmacological criteria

Query iPPI-DB one PPI target at a time and optionally refine your search by choosing some specific pharmacological features, physicochemical characteristics for the compounds or extract only drug candidates.


 By chemical similarity

Sketch your molecule or copy/paste it as a SMILES, choose which fingerprint to use and fetch the 20 closest iPPI-DB compounds to your input along with their binding data.